![]() ![]() The total score is interpreted: (0–7: absence of insomnia 8–14: slight insomnia 15–21: moderate insomnia and 22–28: severe insomnia. ISI scale yields a total score ranging from 0 to 28. First, we evaluated the Insomnia Severity Index (ISI), Hamilton Depression Scale (HAMD), and Symptom Checklist-90 (SCL-90) as a predictor of the effect of insomnia on MDD. The aim of this study was to assess the effect of insomnia on the prognosis of patients with MDD. So, it is crucial to examine the role of insomnia in evaluating the prognosis of MDD. A study has confirmed the importance of insomnia as a risk factor for MDD and the necessity of early treatment of insomnia. Insomnia in people indicates a greater risk for MDD that persists for at least 30 years. It is well known that insomnia is an independent diagnostic entity, which may lead to the development of MDD. Moreover, insomnia is an important predictor of MDD recurrence and may lead to unpleasant clinical outcomes. It is generally agreed that sleep disturbance is a symptom that can be alleviated related to the treatment of MDD. ![]() These observations suggest that it is essential for sleep medicine practitioners to realize patients with MDD and solve their sleep problems. In addition, improving sleep in patients with MDD can improve outcomes. Furthermore, it has been found that depressed patients with sleep disturbance may have more severe symptoms and treatment difficulties. These sleep regulation problems are not secondary to the disorders instead, they precede depressive episodes and persist during remission. Sleep disturbance is one of the most consistent symptoms associated with MDD. In many cases, sleep disorder is the main complaint of MDD. MDD is one of the most commonly diagnosed mental disorders, with a lifetime prevalence of approximately 16%. MDD is a common mental disorder affecting more than 4% of the global population. People with sleep problems are more likely to have mental disorders, such as bipolar disorder, generalized anxiety disorder, and especially major depressive disorder (MDD). ![]() Sleep disorders afflict nearly a quarter of the global population. This study was inspired to assess insomnia as a comorbid disorder for patients with MDD, which may bring poor treatment consequences. The HAMD scores in all groups improved significantly in the 2nd week. The ISI scores of the moderate and severe group decreased significantly ( P < 0.05) in the 2nd week compared to the baseline. Resultsįifty-five patients between 19 and 58 years old, with a diagnosis of MDD via the Structured Clinical Interview for the Diagnostic and Statistical Manual-5 (DSM-5). We evaluated the effect of insomnia at the 2nd, 4th, and 8th-week follow-up on the prognosis of MDD. In addition, we compared the results of the Hamilton Depression Scale (HAMD) and Symptom Checklist-90 (SCL-90) scores. We divided the patients into three groups according to the Insomnia Severity Index (ISI) scores. This study aimed to assess the effect of insomnia on the prognosis of patients with major depressive disorder (MDD). People with sleep problems are more likely to have mental disorders. ![]()
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